- Overview
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BD Phoenix™ panels can be stored at room temperature, are leak-resistant and do not require reagent additions post inoculation.
The BD Phoenix™ Emerge™ Gram-negative and Gram-positive panels offer 136 wells for susceptibility testing, allowing for additional antimicrobial dilutions that help provide the foundation for detecting emerging resistance.
The BD Phoenix™ CPO detect test, offered on certain Gram-negative panels, provides results, including Ambler classification that can support clinicians in making treatment decisions.
BD Phoenix™ panels allow the BD Phoenix™ M50 instrument to determine growth using both an oxidation-reduction reaction and turbidity development, providing both rapid and accurate susceptibility results.
The BD Phoenix™ system utilises on-panel doubling dilutions of antimicrobial concentrations for determination of MIC results.
BD Phoenix™ panels, which require no refrigeration and are leak resistant, are available in a variety of formats including identification-only and susceptibility-only, and in combination identification and susceptibility panels.
With 136 wells dedicated to susceptibility testing, the BD Phoenix™ Emerge™ panel may allow for additional antimicrobial dilutions or additional drugs.
The BD Phoenix™ system provides on-panel doubling dilutions of antimicrobials and built-in detection of resistance, including CPO, MRSA, mecA, VRSA, VRE, ESBL, HLAR, and iMLSb*.
*Depending on BD Phoenix™ panel type and organism identification.
The BD Phoenix™ AP automated inoculation preparation instrument may help to reduce sample preparation workflow burdens, reducing total hands-on time per sample by 50% compared to manual BD Phoenix™.1
- The BD Phoenix™ system offers identification-only panels and combination ID/AST panels, using 51 wells for identification substrates.
- The instrument can provide identification of most clinically significant Gram-negative and Gram- positive bacteria, as well as yeast.
- The BD Phoenix™ system offers 85 wells for antimicrobial dilutions on standard AST-only panels and combination ID/AST panels, and 136 wells on the BD Phoenix™ Emerge™ panel.
- The instrument can provide susceptibility results for most clinically significant Gram-negative and Gram-positive bacteria.
- The BD Phoenix™ system panels test for several resistance markers* such as** :
- Gram-positive bacteria
- HLAR—High Level Aminoglycoside Resistant Enterococcus
- iMLSb—Inducible Clindamycin Resistance
- MRSA—based on Oxacillin Interpretation with Staphylococcus species
- mecA - detection in mecA-mediated resistance Staphylococcus aureus
- BL-Staphylococcus ß-Lactamase (Nitrocefin-based test)
- VRSA—Vancomycin-Resistant Staphylococcus aureus
- VRE—based on Vancomycin interpretation
- Gram-negative bacteria
- CPO—Carbapenemase Producing Organism
- ESBL—offered on Gram-negative panels and requires no additional disc diffusion or E-Test confirmation
- Gram-positive bacteria
* Depending on BD Phoenix™ panel type and organism identification.
- The BD Phoenix™ CPO detect test, available on certain BD Phoenix™ Gram-negative panels, provides information, including Ambler classification, to help guide clinicians in their treatment decisions.
- This test is available in two-panel configurations that allow microbiology labs to test for CPOs as part of routine susceptibility testing on BD Phoenix™ panels:
- 2-well configuration—provides detection of Carbapenemase-producing organisms in Enterobacterales, Pseudomonas aeruginosa and Acinetobacter baumannii
- 9-well configuration—provides detection of Carbapenemase-producing organisms and Ambler classification (A, B or D) in Enterobacterales, Pseudomonas aeruginosa and Acinetobacter baumannii
- The BD Phoenix™ CPO detect test is currently the only phenotypic test on an automated AST system that provides CPO detection and Ambler classification.
- On average, the BD Phoenix™ CPO detect test detects and classifies CPOs from isolated colonies within 6 to 11 hours**.
**BD internal studies—data on file
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*Depending on BD Phoenix™ panel type and organism identification.
References
- Junkins A, et al. Comparison of BD Phoenix AP Workflow with Vitek 2. J. Clin. Microbiol. 2010. 48 (5): 1929-1931. – Study was a supported grant from BD Diagnostic Systems
BD-38368